The ENHANCE Project team strongly believes in sharing the data we collect with the communities that participate in our projects. The data shared on this page is from the first of multiple surveys for the ENHANCE Project, and is not representative of the entire state, a specific group of people, or a particular location in any way. The ENHANCE Project is ongoing, and we plan to continue sharing additional information as we learn more.
The information you see today is from 400 people who use drugs in four cities in Wisconsin and what they told us about their experiences on a survey we did in 2024-25. The ENHANCE Project team is still working to understand what this information means and the impact we may have on helping to fight the overdose crisis.







ENHANCE Research Papers
- Advancing research on strategies to reduce drug use and overdose-related harms: a community informed approach to establishing common data elements
Written by: Lissette M. Saavedra, et. al.
This project brought together researchers, community partners, and people with lived experience to develop a shared set of research measures for harm reduction studies. The resulting framework standardized data collection across 10 research projects, helping researchers compare findings more easily and strengthen evidence on strategies that reduce overdose-related harms
- Exploration of novel harm reduction approaches to increase client engagement (ENHANCE): protocol for a prospective cohort study
Written by: Rachel E. Gicquelais, et. al.
This paper describes the ENHANCE Project, which was designed with input from people who use drugs to better understand how harm reduction services can reduce overdose risk and support health. Early findings showed that overdose experiences and overdose-related risk behaviors were common among participants, highlighting the importance of accessible harm reduction programs.
ENHANCE Research Presentations
- Using Self-Generated Identification Codes to Quantify Syringe Services Program Utilization among Participants of a Prospective Cohort Study
Created by: Caitlin Conway, et. al.
This study examined whether anonymous syringe service program records could be linked with participant survey responses and whether people accurately reported their use of these services. Participants generally reported using syringe services programs more often than was shown in program records, suggesting that some visits may not have been captured in official records.
The ENHANCE Project Team will continue to update this page as we learn new things from our ENHANCE participants. If you have questions, comments, or concerns please contact our study team.
